Erik Lamela is out of Sunday’s trip to Everton with a hamstring injury.
The Argentine international attacking midfielder is undergoing treatment and is unavailable for the trip to Goodison Park.
Defender Jan Vertonghen also has a hamstring problem and is being monitored and assessed ahead of Sunday’s game.
Left-back Danny Rose misses the trip as he serves a one-match ban for an accumulation of yellow cards.
Goalkeeper Hugo Lloris (elbow) is continuing assessment and rehabilitation – he remains out.
Kick-off against the Toffees is at 4.30pm.