Spurs are 4/6 favourites with William Hill to extend their unbeaten home record in the Premier League against Southampton on Sunday. The draw is 5/2 with Saints priced 9/2.
Spurs had won five on the trot at home against the Saints until last season's 3-1 loss. That is their only defeat in the last nine home and away, extending that run in style with a 4-1 win at St Mary's in December.
Southampton are in form coming to the Lane with a 4-0 win at Sunderland and 4-3 win against Watford following a run of six defeats in seven.
Spurs remain unbeaten at home in the Premier League with 12 wins in 14 and still only conceding seven goals. Despite their recent flurry, Saints have only scored 32 goals, one of the worst records outside the bottom three.
Harry Kane will be missing, but Heung-Min Son (14) and Dele Alli (16) have 30 goals between them in all competitions and will be ready to take up the mantle.
Son, who scored a hat-trick against Millwall last week, is 7/2 to score first and 11/10 to score at any time with William Hill. Dele is 4/1 to score first and 5/4 to score at any time.
In-form Christian Eriksen, who opened the scoring against Millwall, is 13/2 to score first, 21/10 to score at any time.
Spurs are 13/2 to win 1-0 and 15/2 to win 2-0 and William Hill offer enhanced odds of 2/1 for a Spurs win with Dele on target.
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