The Swiss international looks set to start his first Premiership match at home in almost a year against Manchester City on Saturday.
Vega is favourite to replace crocked skipper Sol Campbell and is desperate to put a run of games together to prove he has a future at White Hart Lane.
Perhaps that extra pressure has kick-started those nervous tensions. He admitted: "I have mixed feelings and it has been ages since I felt like it, starting a game and it will be strange.
"Of course it is exciting - it is like I am having my first game for Tottenham again like I did for my debut against Manchester United.
"That's the beauty of football. When you are coming out of the tunnel, you hear the fans, it's our crowd as well and that is what I like about football. That's why I am a footballer.
"It is a home game and I loved the reception I had from the fans in the last game against West Ham. They encouraged me a lot and that's what I like. I would like to give the fans back the confidence they have given to me.
"I'm looking forward to that, my problems with injuries are past now and I just want to play well for my club. First I will look to do my job which is to defend and anything on top of that is a bonus."
One bonus will be to keep City's strike force at bay. Vega will face former World player of the year George Weah and the unpredictable Paulo Wanchope at the Lane.
He added: "One is very experienced in George Weah and everybody knows he is a top-class striker.With Wanchope, nobody knows what he is going to do. You have to keep an eye on both of them.
"But we have an excellent team spirit, we are at home and we can do very well against them. I am looking for the win and if the crowd are like they were against West Ham then to win would be perfect."
To listen to Ramon Vega's thoughts, click here
Ramon Vega admits he's starting to feel the butterflies in his stomach again.