Both teams can still win National Group Two of the newly-formed league and meet in their 12th and final match of the first half of the season.
We top the group on goal difference from United - who sit second, having completed their fixtures - and two points clear of Villa in third.
A point will be enough us to clinch top spot although our place in the Elite Group in the second half of the season is all-but secured, barring a double-figure loss tonight.
Villa, meanwhile, need at least a point to have a chance of taking the best third-placed spot in the Elite Group.
"We're sitting top of the league having played the style of football we want to play," said Senior Professional Phase Coach, Chris Ramsey.
"We've also seen players impress and get an opportunity with the first team and that's obviously the main role of the Development squad, so it's worked out well.
"As far as this game goes, we'll go to Villa, look to win and look to top the group. It's all about finishing this first group stage in the right way."
Kick-off is at 7pm tonight - we'll have live updates via @SpursOfficial on Twitter, with a report here on tottenhamhotspur.com later...