We kick-off the Premiership's busy festive programme with a televised home clash against Manchester City tomorrow (3pm) before travelling to West Brom on Monday.
"The next two games for us are going to be very significant," stressed Glenn at Spurs Lodge.
"If you look at the teams we're in there with after a place in Europe I would say Everton are in pole position, but they have a derby match against Liverpool and Chelsea away.
"Blackburn have a derby match against Bolton and they also have United to play.
"We have two games that we have to win and if we're successful it could put a completely different complexion on things.
"It's up to us to get our own business right. It's up to us and then we'll see where that takes us."
Here are the run-ins for the clubs in the European chase:
Everton: Liverpool h 19/4; Chelsea a 21/4; Villa h 26/4; Fulham a 3/5; United h 11/5.
Liverpool: Everton a 19/4; Charlton h 21/4; WBA a 26/4; City h 3/5; Chelsea a 11/5.
Blackburn: United a 19/4; Bolton h 21/4; Leeds a 26/4; WBA h 3/5; Spurs a 11/5.
Spurs: City h 18/4; WBA a 21/4; United h 26/4; Boro a 3/5; Blackburn h 11/5.
Middlesbrough: Arsenal h 19/4; West Ham a 21/4; Birmingham a 26/4; Spurs h 3/5; Bolton a 11/5.
Charlton: Birmingham h 19/4; Liverpool a 21/4; Soton h 26/4; United a 3/5; Fulham h 11/5.
Southampton: Leeds h 19/4; Birmingham a 21/4; Charlton a 26/4; Bolton h 3/5; Arsenal a 7/5; City a 11/5.
Glenn Hoddle believes two wins over the Easter period could put a completely different complexion on the battle for Europe.