The midfield pair played full 90-minute shifts in the Under-21s opening group fixture against Moldova on August 15 and aim for their tenth and sixth caps respectively at this level.
The match will be played at the Stadion Allmend in Luzern with kick-off at 7.30pm local time.
It's a key fixture for Peter Taylor's men following a disappointing 2-2 draw against Moldova at Portman Road.
The qualification process for the finals has been reduced so groups now only consist of three teams with group winners only progressing to play-offs. Anything less than victory and England face early elimination.
Tom Huddlestone and Wayne Routledge have been called up for England Under-21s crucial European Championship qualifier against Switzerland.