The midfielder's 45-minute stint off the bench at the Emirates Stadium on Saturday was his first action since suffering a calf problem at Reading and missing the games against Blackburn, Bayer Leverkusen and Wigan.
But now he's out again. "JJ won't be fit to play," reported Martin Jol on Monday afternoon. "He took a kick on the ankle at Arsenal, it doesn't look right and that's a shame after he just came back from his calf injury."
Edgar Davids, Mido and Anthony Gardner remain out, Hossam Ghaly is suspended but Paul Stalteri looks set to return to the squad after his knee injury at MK Dons in October.
Martin added: "Paul Stalteri will be in the squad, he's trained well and looked fine.
"Edgar Davids has a problem with pressure on his eye again, so he's not in the squad. Mido is out, he's still feeling minor pain in his adductor in his groin and Anthony Gardner is out with his lower back problem."
Jermaine Jenas is out of Tuesday night's clash against Middlesbrough at the Lane after picking up an ankle injury against Arsenal.