The defender picked up a calf injury at Villa on Boxing Day and has missed our last five matches.
"William trained today," said Assistant Head Coach, Steffen Freund, on Friday.
"I’m not sure about (being in) the squad, but William is back after his injury and at the moment, he looks good."
Jan Vertonghen has also trained this week after illness forced him out of the starting line-up against United last weekend.
That means Sandro and Younes Kaboul remain sidelined.