Harry Redknapp will be boosted by the availability of Rafael van der Vaart and Sandro for Saturday's visit of Everton to the Lane.
Both were unavailable for Wednesday's Champions League defeat at Inter Milan through suspension and ineligibility respectively, but they will return to the squad for the clash with David Moyes' side.
The manager is also wary that Wednesday's hat-trick hero Gareth Bale has had little rest in recent weeks and has hinted at making changes as we return to domestic action.
But Harry has confirmed Ledley King remains out with a groin injury, alongside longer-term absentees Jermain Defoe, Michael Dawson, Jonathan Woodgate and Jamie O'Hara.
Giovani Dos Santos has also joined the injury list with groin trouble. Harry said: "People like Ledley are still not fit so there's still a little group of players who are not available.
"But Rafa's available, as is Sandro who can come into midfield for us, so we've got one or two we can change around who didn't play the other night.
"We got back to England at 3.30 in the morning on Thursday so I will look to freshen it up with one or two tomorrow.
"It's a shame we haven't got that four or five who are injured at the moment who would be fantastic for us to play. But we have got some players who are desperate to play, like the boy Sandro and Wilson Palacios who are top players and available."
On man of the moment Gareth, he continued: "He's been fantastic but he's tired to be fair. He had a couple of tough games for Wales, then Saturday at Fulham, then at the San Siro, so we'll see how he is this morning. I think he's nearly running on empty but hopefully there's still a bit of petrol left in there."
And on the progress of Defoe and Dawson, Harry added: "I think Jermain's going well. He's got the protective boot off now so he's certainly progressing quickly.
"Michael will be back as quickly as anyone can be. He's such a fantastic pro and as soon as he's got a chance of being anywhere near, he'll push himself, but he's still quite a way off at the moment."