Harry Redknapp reports that both Rafa van der Vaart and Jermain Defoe are doubtful for Saturday's trip to West Brom.
Rafa is struggling with a hamstring injury while Jermain has a tight groin.
"Rafa has had a hamstring problem on and off this season," said Harry. "He got it playing for Holland but pulled through again to play on Monday against Villa but felt it and came off again.
"He was sore with it yesterday (Thursday) and he's struggling.
"Jermain also has a groin problem and he had to come off training yesterday.
"That leaves us with Pav and Adebayor. Pav's had a back problem but trained yesterday and looks fine."
Niko Kranjcar (thigh), Danny Rose (ankle), Michael Dawson (Achilles) and Tom Huddlestone (ankle) remain sidelined.
Harry said that Jermain has been unlucky not to feature more in the Premier League of late.
"Jermain's a fantastic player," added the manager. "We had a reserve game in midweek against Charlton, he scored five goals and they were all incredible finishes.
"He's just been unlucky. I've said all along, Emmanuel Adebayor came in and has been great up front and I've Jermain or Rafa to play with him.
"Jermain was in good form at the time but Rafa has been in fantastic form, his goalscoring has been top-class.
"Jermain has been unlucky and so have a few of the other lads, but the team is playing well and I can't change it."