Ben Thatcher has been laid low by a virus all week, Neil Sullivan and Christian Ziege returned from international duty with knocks and missed our Easter programme while Ledley King picked up a slight ankle problem at Middlesbrough.
"They still have some way to go to be fit for Saturday," said boss Glenn Hoddle. "We have a problem in that even if players play, they won't be 100 per cent fit."
Les Ferdinand is added to the list after fracturing his wrist in a freak accident and he now looks likely to miss the rest of the season.
Mauricio Taricco is suspended but better news saw Gary Doherty, Stephen Clemence, Oyvind Leonhardsen and Chris Armstrong back in reserve team action in midweek.
Arsenal welcome back Tony Adams, Ray Parlour and Lauren.
Parlour, out for a month after suffering an ankle injury in training, came through the full 90 minutes in Wednesday night's reserve win over Charlton and could be recalled to the starting line up.
Adams' return to fitness gives Arsene Wenger the opportunity of choosing between him and Martin Keown to partner Sol Campbell at the heart of the defence.
Four players are fighting to be fit in time for the big one at Highbury.