Midfielders Darren and Simon miss out with Achilles and shin injuries respectively, defender Dean also has Achilles trouble and goalkeeper Rob will be sidelined for at least another fortnight with an ankle injury.
Skipper Jamie Redknapp, who returned to action against Newcastle as a substitute last week, is in the squad alongside youngster Dean Marney.
Acting boss David Pleat said this afternoon: "The major players not travelling are Darren Anderton, Simon Davies and Dean Richards.
"We hope Simon will manage a full week's training next week and soon be available again as he's an important player for us.
"Dean Marney is added to the squad, we have 19 players travelling and hope the 11 who start for us do themselves justice."
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Darren Anderton, Simon Davies, Dean Richards and Robert Burch are the only players to miss tomorrow's trip to Old Trafford through injury.