Helder Postiga (hamstring) and Darren Anderton (Achilles) miss out while Mauricio Taricco remains a doubt after picking up a foot injury against Fulham.
Jamie Redknapp is unlikely to be involved at first team level yet despite completing 65 minutes on Monday night in his second reserve outing after knee surgery.
Better news sees Gary Doherty closing in on full fitness after making it back to the bench against Portsmouth on Saturday.
Youngsters Mark Yeates and Lee Barnard are expected to be named in the squad.
Acting boss David said: "We've got a few knocks and bruises. We won't know the team until the last minute but whatever it is, it will be giving it's all for Tottenham Hotspur."
David Pleat reports a 'few knocks and bruises' as he prepares for tomorrow night's Premiership clash at Charlton.