The Moroccan international was back on the bench last time out at Highbury after hamstring trouble but suffered this latest blow in training this week.
"Naybet has an ankle injury," reported Head Coach Martin this afternoon. "He was fit last week after his hamstring problem but hadn't played for three or four weeks, so he didn't have a lot of match practice.
"Michael Dawson was in a good way so I left Naybet on the bench (at Arsenal). Now it's a different matter - he has an ankle problem."
Pedro Mendes (broken toe), Noe Pamarot (knee), Anthony Gardner and Michael Brown (both foot) all remain out.
"Michael is out for the season, Pedro Mendes the same," added Martin. "Noe Pamarot might be out for another six months and Anthony Gardner faces a problem for the rest of the season with his foot injury."
Noureddine Naybet has picked up an ankle injury and looks doubtful for Sunday's clash against Villa.