Michael Dawson and Roman Pavlyuchenko have been ruled out of Saturday's trip to Manchester United in the Barclays Premier League.
Defender 'Daws' is awaiting results of a scan on the ankle injury he picked up in last weekend's victory over Newcastle.
Striker ‘Pav', meanwhile, remains out with a back injury, although a scan has revealed no serious damage.
Manager Harry Redknapp will also assess the fitness of Ledley King ahead of the Old Trafford clash, after the defender sat out the Newcastle win.
"We will see how Ledley is in training and just take it from there. If there is a doubt I won't risk him but if he is ok he will play," said Harry in today's press conference at Spurs Lodge.
Striker Fraizer Campbell is also unavailable to face his parent club due to the terms of his loan deal from United.