The big defender picked up a knee injury in last weekend's fourth round replay win against West Brom and joins cup-tied ex-Forest pair Andy Reid and Michael Dawson on the sidelines.
After his two-goal debut against Portsmouth a fortnight ago, Mido wasn't eligible for the replay against West Brom but returns to the squad for Forest.
Sean Davis is on his way back after knee surgery in November having played an hour in a training ground friendly against Wycombe on Wednesday but not yet ready for a full return.
Head Coach Martin Jol reported this afternoon: "Anthony is out, 90 per cent. In the last game he had a knock and a swelling on his knee.
"Sean Davis is fit, played for the reserves this week, will hopefully play the next match for the reserves (Charlton away on Monday) and then in one or two weeks time will be available.
"Mido is available. He had a knock on his hip this morning but I don't think it's a big problem."
Anthony Gardner is out of Sunday's FA Cup fifth round tie against Forest but striker Mido is now eligible to play.