Striker and stand-in skipper Robbie is fighting to be fit after turning his ankle over against Bolton last weekend.
Midfielder Michael also picked up a ankle/calf problem against Bolton while Mido has been out for almost a month with first groin and now a knee injury.
Head Coach Martin Jol reported on Friday: "Robbie maybe has a small chance and we'll try him again tomorrow but I think it's still a 90/10 chance against that he'll make it.
"Michael will hopefully be okay, he hasn't trained this week but hopefully he'll train tomorrow and will have a late test.
"Mido hasn't trained now for three weeks but we will try to do something tomorrow and have another late test."
Unfortunately, full-back Paul Stalteri has been ruled out with a knee ligament problem and he will join Ledley King (broken fourth metatarsal, left foot) and Jermaine Jenas (shin) on the sidelines.
Asked if he would risk any players, Martin responded: "No, but if Robbie tells me he's fine you take a risk anyway because you would normally be out for a couple of weeks."
Better news is that Danny Murphy has recovered from a knock against Bolton and Edgar Davids is back from suspension.
Robbie Keane, Michael Carrick and Mido will all undergo late fitness tests before Sunday's crunch Premiership finale at West Ham.