All eyes will be on last season's goalscoring hero Harry Kane, who scored just over half of his 31 goals in all competitions in front of the Spurs fans.
If you fancy Harry to score first and Spurs to win 3-0, Marathonbet offer a healthy 60/1! If you think Harry can grab a double, it's 61/20.
Nacer Chadli scored a spectacular volley in last season's encounter between the teams at the Lane and he's 113/50 to repeat the feat and score at anytime.
Over 70% of Spurs' Premier League matches had over 2.5 goals last season and for Mauricio Pochettino's men to come out on top this time with over 2.5 goals is 15/8.
If you're expecting a tight first half, perhaps go for a draw first half/Spurs FT win at 77/20. Spurs to win to nil, meanwhile, is 51/25.
It's always competitive against Stoke and if you fancy a different bet, the Potters are 5/6 to be given the most yellow cards.
Find more odds with Marathonbet now.