The Swiss international completed his first hour of pre-season action in Thursday's 1-1 draw against Boreham Wood.
Coach Clive Allen said: "Reto worked hard. He's about a week behind everyone after playing for Switzerland in the summer and that was the reason he only played for the hour.
"He wanted to to carry on but with another game coming so soon it was important he came through with no ill effects. He looks fit and strong, hasn't lost too much fitness and will now push on again on Saturday."
It's a step up in terms of opposition for the Spurs XI squad with Cambridge City finishing second in the Conference South last season. Kick-off is 3pm.
Spurs XI squad: Forecast, Button, Kyriacou, Daniels, Lee, Mills, Lewis, O'Hara, Ziegler, Davis, Hallfredsson, Barcham, Maghoma, Hamed, Wells, Riley.
Reto Ziegler will again skipper our Spurs XI side in Saturday's friendly against Cambridge City at Milton Road.