The defensive duo missed the majority of our pre-season matches and the Premiership opener at Birmingham City on Saturday through injury.
Ledley damaged his ankle in the pre-season opener at Stevenage Borough while Dean has been troubled by an ongoing Achilles problem.
However, both have trained for the last week without problems and now both return to form a formidable central defensive trio alongside Chris Perry in our second FA Premier Reserve League game of the season.
Colin Calderwood's side picked up a point in a 1-1 draw at Leicester City last week.
Squad: Sullivan, Marney, Richards, King, Perry, McKie, Hughes, Jackson, Barnett, Slabber, Barnard, Henry, Burch, O'Donoghue, Black, Malcolm.
Dean Richards and Ledley King are set to make their comebacks for the reserves against Portsmouth at Havant & Waterlooville tomorrow night.