Loic Remy grabbed the only goal in the 12th minute of the Premier League encounter.
It was one-way traffic in the second half as the team clicked into gear, but there was no way past an inspired Tim Krul in the Newcastle goal.
Krul had already produced world-class saves to deny Roberto Soldado and Paulinho in the first half and it was his afternoon, eventually racking up 14 saves as we fired in 31 efforts at his goal.
Krul’s best save came on 53 minutes, when he changed direction to keep out Gylfi Sigurdsson’s free-kick, then managed to block Younes Kaboul’s follow-up from inside the six-yard box. As the ball looped up, defender Mapou Yanga-Mbiwa somehow hooked off the line.
When Krul was beaten, Jan Vertonghen’s bullet header from Christian Eriksen’s corner rattled the crossbar six minutes from time.
“I think we were unlucky, but we didn’t have a good first half,” reflected Andre.
“We gave Newcastle that advantage and paid the price.
“I’m particularly happy with how we reacted in the second half and we were very unlucky not to score at least one goal.
“Tim Krul made a difference, managed to keep Newcastle alive and take the win.
“They were outstanding situations and normally one goes into the back of the net and the lift you get from scoring is immense. It wasn’t to be. Krul made one save after another, we hit the bar. It wasn’t to be our day.”