Harry Redknapp's men are 17/20
favourites with the draw going at 13/5
but will be aware that their 11 Premier League trips to the Reebok have seen Spurs claim just four draws and no wins.
Recent history however is no match for this season's form and with the Trotters having lost 10 of their 17 home matches this as well as conceding 33 home goals - the highest in the division behind Wolves - Tottenham can fire in a seventh away win of the term to put the pressure on Arsenal.
Rafael van der Vaart is 13/2
to open the scoring after netting first in the weekend victory over Blackburn while Emmanuel Adebayor is 9/2
favourite to score first. A fantastic performance from Sandro on Sunday cannot be overlooked though and after the Brazilian came to within inches of a 25-yard opening goal cracker at the Lane, the 20/1
on him scoring first looks a decent bet.
With Newcastle and Chelsea also playing each other tonight, a big win for Spurs could also prove pivotal in the goal difference standings come the final day of the season and both over 2.5 goals at 13/20
and over 3.5 goals at 9/5
are worth a look at.
Spurs have scored three goals exactly in the two meetings with Bolton this season and can be backed to score more than 2.5 goals on their own at 5/2
while a repeat of the 3-0 league meeting is priced up at 14/1
Those supporters expecting a nervy first half only to cheer on a vital Tottenham victory may be enticed by the 21/20
that Spurs win the second half, or even the huge 25/1
price in the double result market for Bolton to be winning at half time and Spurs to win the game.
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Spurs can move to within a point of North London rivals Arsenal tonight but will have to break with recent history if they're to get all three points at the Reebok.