Harry marked his 100th game with the opening goal but Mousa's outstanding display in midfield certainly caught the eye - he was singled out for praise by ex-Spur Jermaine Jenas on Match of the Day on Saturday night.
Almost 15,000 votes were registered on the MOTM poll on Twitter, Facebook and the Match Centre here on tottenhamhotspur.com.
MAN OF THE MATCH RESULT - SOUTHAMPTON
Mousa Dembele - 47.44%
Harry Kane - 39.22%
Toby Alderweireld - 13.34%
Thanks for voting!