The tie will be played over two legs, with the winners advancing to the final at Wembley to face either Chelsea or Liverpool.
The dates have been confirmed as follows...
Wednesday, January 21 – Tottenham Hotspur v Sheffield United (kick-off 7.45)
Wednesday, January 28 – Sheffield United v Tottenham Hotspur (kick-off 7.45)
Ticket information will be confirmed in due course.