With players involved in either Wednesday night's first team and the youth team that beat Blackburn on Tuesday unavailable to him, Colin was forced to mix and match to put together a team.
By contrast, Charlton fielded only two players without significant first team experience and had names like Mark Kinsella, Eddie Youds, Richard Rufus, Jonatan Johansson and John Robinson on show. Add South African international Shaun Bartlett, who came off the bench to some effect and Charlton had a pretty potent mix.
A major boost for Spurs was Stephen Clemence successfully coming through a third reserve game and Gary Doherty making his return as a half-time substitute.
After a fairly even first half in which Yannick Kamanan was unlucky with a number of chances, the best one being when he hit the bar from a Matthew Etherington cross.
It was Spurs who took the lead on the hour, a brilliant interchange between Johnnie Jackson and George Snee led to Jackson thumping in a powerful low first time shot that beat Sasa Ilic down to his right.
The celebrations did not last long however, and a minute later Johannson sped into the area and unleashed a low rasping drive beyond Kasey Keller and just inside his left hand post.
Five minutes later a long ball in from the right found the head of Bartlett who headed goalwards. Keller was off his line and acrobatically got a hand to the effort, but could not prevent the ball trickling in.
Spurs battled gamely and should have levelled when Doherty powered the ball home from a Etherington cross. Unfortunately for the Doc on his comeback, the linesman dubiously ruled offside.
Clemence fired in two efforts late on, but Charlton broke away two minutes into stoppage time and Lisbie on the right fed the ball into Bartlett who prodded in his second and Charlton's third.
Team: Keller, Jacobsen (Consorti 56), Quilter, Toner, Thelwell, Clemence, Snee, Jackson, Vedeux (Doherty 45), Kamanan, Etherington (Herron 84).
Charlton: Ilic, Kishishev, Lewis (Bartlett 45), Youds (Martin 60), Rufus, Brown (Turner 17), Collis, Kinsella, Lisbie, Johansson, Robinson.
Colin Calderwood's patched up reserve side fell to a 3-1 defeat at Charlton despite playing well and going a goal up through Johnnie Jackson.