The midfielder has been out since early October with an ankle injury and last tasted first team action in the Europa League draw against Besiktas on October 2.
“It’s good news for us, good news for Nabil,” said Mauricio Pochettino after training on Wednesday. “He’s an important player for us and great he’s back in the squad.”
Kyle Naughton is available for European football as he serves a two-match ban in the Premier League but Federico Fazio is suspended after his red card in Matchday Four against Asteras Tripolis.
A number of players missed Sunday’s 2-1 win at Hull including Nacer Chadli, Younes Kaboul, Emmanuel Adebayor, Andros Townsend, Etienne Capoue and Danny Rose.
“We need to analyse each case, maybe some players will be available for the weekend,” added Mauricio.