Facing a tough opening fixture, our lads settled quickly and dominated the early proceedings with Alex Pritchard going close in the 12th minute as his powerful strike zipped just wide of the right-hand post.
Despite our early pressure it was Wolfsburg who took the lead as Philip Hauck coolly converted from the penalty spot after Alex McQueen was adjudged to have upended his opponent in the box.
Alex Inglethorpe's side reacted positively to going behind and it was a real surprise that they went into the break with a one-goal defecit as first Milos Veljkovic forced a fine save from Carl Klaus in the Wolfsburg goal and then Souleymane Coulibaly twice went close.
Needing to push for the equaliser in the second half against a physical German side, Shaq Coulthirst was introduced from the bench and he made an impact within minutes as his deflected effort from outside the penalty area left Klaus stranded and brought the scores level at 1-1.
Dominant in the air all night, Spurs goalkeeper Lawrence Vigouroux made sure the scores remained level with a fantastic save in the 66th minute, making himself an imposing figure and saving with his chest at close range from Maimilian Arnold.
It was to be another substitute who would earn us a well-deserved lead.
Ruben Lameiras was introduced in the 75th minute and by the time the clock had reached 77 minutes he was on the scoresheet. Coulibaly forced a fine save from Klaus, however, Lameiras was the sharpest to react and volleyed the ball into the roof of the net to make it 2-1.
There was still time for the excellent Pritchard to find the net as his free-kick from 20 yards was too much for Klaus to handle.
Wolfsburg were able to pull back a consolation goal in stoppage time through Julian Brandt, however it was our lads that came out on top with a thoroughly deserved win.
The victory leaves us top of Group One with our next fixture against Barcelona at White Hart Lane on Thursday, September 13 - CLICK HERE for ticket details...
Spurs (4-2-3-1): Vigouroux; A McQueen, Ball (Ogilvie, 67), Veljkovic, Stewart; Gallifuoco (Coulthirst, 60), Dombaxe; McEvoy (Lameiras, 75), Bentaleb, Pritchard; Coulibaly. Unused subs: McGee, D McQueen.
With thanks to Alex Carroll in Wolfsburg...