The lads didn't get off to the most impressive starts in the all-new league at Newcastle's training ground.
They were 2-0 down inside five minutes and after Ryan Mason fired home a fine response, found themselves 5-1 down at half-time.
However. they were the better team in the second half and although Newcastle made it 6-1 on 67 minutes, Yago Falque and Cristian Ceballos sparked a recovery.
Ceballos set-up Falque for 6-2 on 69 minutes and Falque returned the compliment seven minutes later, crossing to the far post for Ceballos to head home for 6-3.
Ceballos then released Falque again to make it 6-4 with 12 minutes remaining and there were further chances as Souleymane Coulibaly twice fired straight at the goalkeeper in the final minutes.
Spurs U21s (4-2-3-1): Miles; Smith (Bush, 16; Onomah, 70), Ekong, Hall, Byrne; Carroll, Mason; Falque, Munns, Ceballos; Coulibaly.