The competition will now adopt a straight knockout format with no more replays taking place, while a fourth substitute has also been introduced for the quarter-finals, semi-finals and final.
The removal of replays means our quarter-final against Millwall will have to be settled on Sunday. Should the scores be level after 90 minutes, extra time and penalties will be used if required.
The additional substitution rule only applies once the game goes into extra time. Managers will now be able to use a fourth substitute from their bench during the extra half hour.
Meanwhile, the draw for the FA Cup semi-finals will take place after Chelsea's match against Manchester United at Stamford Bridge on Monday.
Middlesbrough v Manchester City (Saturday, 12.15pm)
Arsenal v Lincoln City (Saturday, 5.30pm)
SPURS v MILWALL (Sunday, 2pm)
Chelsea v Manchester United (Monday, 7.45pm)