Given their recent form in this fixture, Spurs are available at 28/5 to win Sunday’s match by two goals.
However, all four of the last meetings between the two sides have only been separated by a solitary goal – a repeat of which is available at 57/20 for a home win.
Playing with confidence, Southampton will arrive looking to win and that should allow Mauricio Pochettino’s side plenty of opportunity to get forward.
A Spurs win or draw with under 2.5 goals is 41/10.
Find more Tottenham Hotspur v Southampton odds with Marathonbet.