Manchester City were comprehensive winners against the North London side last season – winning their two league fixtures by an aggregate margin of 11-1.
However, the visitors will be up for the challenge of facing the title holders with Pochettino’s men unbeaten in their last four games – in addition to the potential absence of Yaya Toure in the heart of the champions’ midfield.
Nacer Chadli has been making his presence felt this season and City will do well to quieten the lively midfield man. Involved in five of Tottenham Hotspur’s nine Premier League goals this season – he has four goals and an assist – the Belgian is 5/1 to score anytime.
City are winless in their last two home league games and last went three games without a win in 2010. As such, Pochettino’s men are 36/5 to leave with three points.
Find more Manchester City v Tottenham Hotspur odds at Marathonbet.