The Blues, the league leaders, could only manage a draw away to Southampton on Sunday, so they’ll be keen to return to winning ways to keep second-placed Manchester City at bay.
Indebted to Hugo Lloris’ first-half heroics against Robin van Persie and co. on Sunday, Spurs will no doubt be keen for the action to be at the other end of the pitch against Chelsea and will look to the always lively Harry Kane - 9/5 to score anytime - up front to cause their London rivals problems.
When Spurs last met Jose Mourinho’s men at the Lane it ended in a 1-1 draw and a repeat is currently 34/5.
At 39/50, both teams to score deserves consideration while an opening Spurs goal followed by a home win is 49/10.
Given it will be a hotly contested London derby, it may also be worth taking advantage of the 3/1 anytime (or 9/1 first) offer on Christian Eriksen to score, given that he is Spurs’ set-piece specialist.
Find more Tottenham Hotspur v Chelsea odds at Marathonbet.co.uk
*Prices correct at time of publishing and are subject to change.