The ladies had gone three matches without victory in the FA Women's Premier League but came away from Uxbridge with the type of win that could take them places this season.
Still competing in three cup competitions, with the FA Women's Cup to follow, Spurs are just behind the front runners in the FAWPL South but within touching distance of the top three. Cardiff, however, are flying with eight wins in 10 and currently four points clear at the top.
Bianca Baptiste scored the only goal of the game on 66 minutes, racing onto Kelley Blanchflower's pass to finish in style past QPR goalkeeper Sophie Cheadle.
"We were in control in the first half and had lots of possession without really threatening," reflected manager Karen Hills.
"We had a few words at half-time and our game was more intense in the second half. We wanted it a bit more.
"We made a couple of changes. Kelley Blanchflower came on, injected some energy and set-up Bianca for the goal.
"Wendy Martin also came on for her first game back after injury and she added a real calmness to our game. She's an important player for us.
"Chloe Morgan still had to make one fantastic one-on-one save late on and she impressed throughout. Maya Vio was also excellent in midfield, her pass completion was was spot on.
"It was one of those games where you just need to get the job done and we did that. It was a big win for us."
Spurs Ladies v QPR: Chloe Morgan, Sophie McLean (Mollie Kmia 80), Alex Keown, Leah Rawle, Lucia Leon, Shannon Moloney, Maya Vio, Megan Wynne (Wendy Martin 65), Avilla Bergin (Kelley Blanchflower 55), Katie O'Leary, Bianca Baptsite. Substitute (unused): Toni-Anne Wayne.
FIXTURE CHANGE - SUNDAY
Spurs Ladies will now play West Ham at home in the FAWPL South on Sunday at Cheshunt FC (2pm).
RESERVES ON FIRE
Spurs Ladies Reserves made it seven wins in seven at the top of the FAWPL Reserve Division South with a 14-0 victory at Southampton on Sunday.
Ronnell Humes led the way with five goals, Dionne Manning hit a hat-trick with Amy Cooper (2), Leanne Mabey, Emily Masters and Deanna Brunyee also on target.
INTERNATIONAL GOALS FOR AVILLA
Avilla Bergin scored twice as Northern Ireland beat Georgia 3-0 in Euro 2017 qualifying on October 24.