JD, winning his 50th cap for England, struck the third goal as Roy Hodgson's team made a convincing start to their World Cup qualification campaign with a 5-0 win over Moldova in Chisinau.
In Cardiff, Vertonghen scored with a thunderous free-kick late on to seal Belgium a 2-0 win over Wales in Cardiff. Mousa Dembele and Gareth Bale made up the Spurs contingent in the match, with the latter forcing a fingertip save with a fiercely driven shot as Wales searched for an equaliser after Vincent Kompany put Belgium ahead just before half-time.
Dempsey got the USA off to a superb start in their match against Jamaica with a goal after only 36 seconds, but Jurgen Klinsmann's team fell to a surprising 2-1 defeat in Kingston.
France got their campaign off to a winning start with a 1-0 win over Finland in Helsinki with Hugo Lloris in goal for Les Bleus.
And finally, Iceland ended an 11-game, 25-year wait for a win over Norway with a surprise 2-0 win over their Group E World Cup qualification rivals in Reykjavik. Gylfi Sigurdsson played the full match and it was his long pass that Alfred Finnbogason ran onto to ensure Iceland's victory.