The winger made his debut at Under-21 level as a substitute in the first leg of the Euro 2013 play-offs last month and was handed a full debut for the friendly at Blackpool's Bloomfield Road.
Adam Smith also started at full-back, earning his seventh cap at Under-21 level.
Andros had an early shot saved by Conor Devlin and was involved in the first goal. He was brought down, Jordan Henderson whipped in the free-kick and Connor Wickham powered home his header.
Both Andros and Adam departed after 60 minutes and England completed their 2-0 win as Benik Afobe converted from the penalty spot in the 77th minute.
The seniors take over on Wednesday night, when we've six players in friendly action.
Tom Huddlestone has joined Steven Caulker in the full England squad to take on Sweden in Stockholm.
Steven is looking for his first cap in his second call-up while Tom is after a first cap since May, 2010 to add to his three at senior level.
Emmanuel Adebayor has travelled to Morocco for a friendly with Togo, Hugo Lloris and France have a stand-out friendly in Italy and Jan Vertonghen's eye-catching Belgium team travel to Romania.
Further afield, Sandro has travelled to New Jersey, USA for a friendly against Colombia at the MetLife Stadium, home of NFL teams the Jets and Giants and host of the 2014 Super Bowl.
Meanwhile, Jordan Archer is with Scotland Under-21s for a friendly in Portugal and Nabil Bentaleb is with the France Under-19 squad for a friendly against Germany.