Tom and Harry will no doubt be looking to get one over team-mate and Scottish goalkeeper Jordan when England and Scotland meet at Sheffield United's Bramall Lane. Kick-off is 7.30pm.
Tom will be looking to add to his one cap at U21 level, while Harry is looking for his first U21 cap after representing the U20s in the FIFA U20 World Cup in the summer.
Meanwhile, Jordan will aim for a seventh cap at U21 level for Scotland.
The action continues on Wednesday with another eight players on duty.
The Spurs focus will be in Belgium, where Jan Vertoghen, Mousa Dembele and Nacer Chadli have been called-up for the Belgian squad to take on Hugo Lloris' France.
Jermain Defoe and Kyle Walker are in the England squad to face Scotland at Wembley.
Paulinho is back with Brazil after their success in the Confederations Cup with a friendly in Switzerland while Gylfi Sigurdsson is with Iceland, who take on the Faroe Islands.
Gareth Bale has joined the Wales squad and will train but take no part in Wednesday's friendly against the Rebublic of Ireland.