Harry Redknapp reported that Aaron Lennon was lost to illness just before kick-off at the Bernabeu.
The manager said the winger 'hadn't been feeling great all day' and had to be replaced by Jermaine Jenas as we ended up losing the Champions League quarter-final, first leg 4-0 against Real Madrid.
"We lost Aaron just as the teams were walking on the pitch," said Harry. "He didn't feel well enough to play so we had to change straight away.
"He hadn't been feeling great all day. I said 'are you ok?' and he said 'I don't feel like I have any strength or energy to run', so I had to pull him out.
"He went out to warm-up, came in and just said he didn't feel well and wasn't fit enough to play. There is nothing you can do."
Vedran Corluka later limped off with an ankle injury, adding to Harry's defensive worries with Stoke next up in the Premier League on Saturday.