The striker turned his ankle in a challenge and was stretchered off late in Sunday's Premier League match against Sunderland having earlier scored the only goal of the game.
"Harry has an ankle ligament injury and we will see, we need to assess him every day but at the moment, we cannot give a time for him to be available again," reported Mauricio after training on Tuesday.
Mauricio also said Eric Dier and Mousa Dembele would undergo scans today after both left the action early against Sunderland. "We will have to wait and see but I don't think there will be a big issue," he added.
Harry's absence looks set to hand a starting chance to fellow striker Vincent Janssen as we prepare to face Gillingham in the EFL third round at the Lane tomorrow evening (8pm).
Mauricio added: "It's important to have a strong squad and when something like this happens, the players are all ready to play and compete."
Meanwhile, Danny Rose continues his recovery from a hamstring injury.
GRAB WEDNESDAY'S OFFICIAL MATCHDAY PROGRAMME!
Pick up your copy of our official matchday programme at the Gillingham game on Wednesday night.
Available from several locations around the ground and from the Spurs Megastore, it’s £3.50 for 100 pages, including...
- Feature interview with Ben Davies
- Mauricio Pochettino's exclusive column
- A chat with Gillingham manager and ex-Spur Justin Edinburgh
- Jeepers keepers! Meet the seven goalkeepers who played for both clubs
- Centre of Attention: The lowdown on young midfielder Harry Winks
- Nostalgia, news, stats, academy latest and much more!
Sample it now for free with our 12-page online preview edition
and don't forget to buy yours at the game!
Full 100-page digital editions and subscriptions can also be bought via tottenhamhotspur.com/programme