The midfielder backheeled into the path of Liverpool's Daniel Sturridge, who planted home the winner two minutes into added time.
The result lifts England to the top of Group B with one round of matches remaining.
All five of our players started again with Dele joined by Eric Dier, Harry Kane, Danny Rose and Kyle Walker while Ben Davies lined-up for Wales.
Gareth Bale fired Wales ahead, Jamie Vardy - on for Harry at half-time - levelled and having dominated, Sturridge, also on at the break for Raheem Sterling, found the dramatic winner.
Below: Kyle celebrates the winner
Kyle was particularly impressive and later voted Man of the Match by UEFA.
England top the table on four points with Wales and Slovakia on three and Russia on one.
The final group matches see England take on Slovakia in Saint Etienne and Wales face Russia in Toulouse - both at 8pm UK on Monday.