We first locked horns at Upton Park over a century ago and we've certainly experienced the full range of emotions in East London since.
That drama has laid out in three last-minute victories in the last 10 years.
Paul Stalteri struck late to win an incredible game on March 4, 2007.
We trailed 2-0 that day before Jermain Defoe and Teemu Tainio levelled it up in the second half. However, it looked game over when Bobby Zamora restored West Ham's lead five minutes from time, but we should have known better.
Dimitar Berbatov clipped home the equaliser from a free-kick in the 89th minute and as West Ham pushed for a winner, we broke away, Jermain Defoe's shot was saved but Paul Stalteri - of all people - was there to slot home.
It was a similar story on February 25, 2013. Gareth Bale fired us ahead only for West Ham to hit back and lead just before the hour.
Once again, we hit back. Gylfi Sigurdsson levelled it up before Bale's moment of magic, a 30-yard beauty that flew into the top corner in the 90th minute to secure a 3-2 win.
We only have to go back to last season for our last visit and last moment to remember. This time, having played with 10 men since the half-hour, Harry Kane released a rampaging Eric Dier in the 90th minute who finished in style - on his debut - to bag the three points.
Watch all three at the top of the page!
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