We lost out to the Serie A side at this stage of the competition last season, going out 3-1 on aggregate.
The dates for the two-legged tie are not confirmed but are scheduled for Thursday, February 18, and Thursday, February 25.
The draw took place in Nyon, Switzerland at 12 noon today (Monday, December 14).
Having topped our qualifying group, we were one of the 16 seeds alongside 11 fellow group winners and the four best third-placed teams from Champions League qualifying.
Seeded teams were drawn against unseeded teams and as a seeded team, we will play at home in the second leg.
Here is the draw for the round of 32 in full:
Valencia (ESP) v Rapid Wien (E, AUT)
Fiorentina (I, ITA) v Tottenham Hotspur (J, ENG)
Borussia Dortmund (C, GER) v Porto (POR)
Fenerbahçe (A, TUR) v Lokomotiv Moskva (H, RUS)
Anderlecht (J, BEL) v Olympiacos (GRE)
Midtjylland (D, DEN) v Manchester United (ENG)
Augsburg (L, GER) v Liverpool (B, ENG)
Sparta Praha (K, CZE) v Krasnodar (C, RUS)
Galatasaray (TUR) v Lazio (G, ITA)
Sion (B, SUI) v Braga (F, POR)
Shakhtar Donetsk (UKR) v Schalke (K, GER)
Marseille (F, FRA) v Athletic Bilbao (L, ESP)
Sevilla (ESP, holders) v Molde (Group A, NOR)
Sporting CP (H, POR) v Bayer Leverkusen (GER)
Villarreal (E, ESP) v Napoli (D, ITA)
St-Étienne (G, FRA) v Basel (I, SUI)