Yehven Konoplyanka slotted home a penalty 10 minutes from time to hand the Ukraine Premier League side the advantage half-way through our Round of 32 tie.
In an open, end-to-end encounter, both teams missed chances and both goalkeepers made saves before Jan Vertonghen was penalised for a trip on Matheus and Konoplyanka did the rest from the penalty spot.
It’s certainly all to play for in the second leg at White Hart Lane next Thursday, February 27.
“I can’t fault the endeavour and application from the lads, we just needed a little more quality at certain times,” said Head Coach Tim.
“You have to give Dnipro credit, they played well. We knew they were a good side with full internationals. We had to show them respect and we did that.
“I thought we could have played better, Brad made too many saves for my liking and that’s what I told the lads. They know they can do better.
“The positive thing is we’re still in the tie, we’ll bring them back to the Lane next Thursday and hopefully we’ll stay in the competition.”