The Welsh midfielder - nicknamed 'Digger' - is back in the squad after summer surgery and hoping to return to action in the televised Premiership clash against the Canaries at the Lane.
If he does, he should come face-to-face with left-back Drury, a player he came through the YTS ranks with at Peterborough United.
The pair, who first met as youngsters at Norwich, eventually spent two successful years in the first team at Posh before Simon and Matthew Etherington moved to Spurs in December 1999. Adam stayed for another two years before his switch to Norfolk.
"I first met Adam when I was about 11 and he was a couple of years older then me," recalled Simon.
"When we were together at Peterborough we were basically in the same team all the way through.
"He was a YTS two years before I got there as a YTS and then he got into the first team before me.
"We played together for about six, seven years in all and in the first team for a couple of years.
"We always used to hang out together, play golf and it was a tight group of mates there. It was a shame we got broken up but it was always inevitable.
"It will be good to see him again. We all keep in touch but this is the first time I'll have played against him.
"I spoke to him earlier in the week. He's going through what I went through when I first came to Spurs. Suddenly you are up against all the big names in front of the big crowds and he's loving it - and he's deserved it, definitely."
Drury also remembers those early days. "The first time I was at Norwich as a young lad Simon was there too, so I've known him a very long time," he said.
"We both left and went to Peterborough and from there we grew-up and learned to play football together.
"I've stayed in touch with him ever since he moved away. I still speak to him and give him plenty of stick when we get together.
"He has been a bit unlucky with injuries but he's a top quality player, as all the players are at Spurs. I'm sure we'll see that on Sunday and it's going to be another very tough game for us."
And they both have their thoughts on potentially playing against each other on Sunday.
Simon smiled: "He has the biggest bow-leg you've ever seen and everyone will see that on Sunday. If I get the chance to play against him one thing I'll be trying to do is nutmeg him!"
Drury added: "When you are on the pitch you tend to forget about being friends. You are professionals and you have to get on with your job on the field. He always used to try and nutmeg me in training, but he didn't often manage it!"
Simon Davies hopes he's lining-up against his friend and Norwich City captain Adam Drury this afternoon.