Juande Ramos was again left to rue the 'penalty' that wasn't as we fell to defeat at Fratton Park on Sunday.
Portsmouth took the lead after 34 minutes when Jermaine Jenas handled Glen Little's free-kick and Jermain Defoe drilled home the spot kick.
If that looked a straight forward penalty award for referee Mike Dean there appeared to be little doubt that Aaron Lennon's cross was blocked by the hand of Lassana Diarra after 54 minutes.
However, this time the award was a corner, much to the dismay of Lennon, all his team-mates in the area and 2,000-plus Spurs fans behind the goal who had the best view in the house.
Just over 10 minutes later and Peter Crouch headed home for 2-0 and it was game over.
It was a repeat of last week when penalty appeals against Wigan following Maynor Figueroa's trip on Lennon were waved away and it ended goalless at the Lane.
"For me, it was the difference," said a naturally disappointed Juande afterwards. "The match was 0-0 when the referee whistled for the first penalty and yet when the same thing happened in the second half, there was no whistle.
"The same thing happened last week against Wigan - we all thought it was a penalty then, but no whistle. It is very difficult."
Would it have been a different outcome? "You never know if we would have gone on to win from there but if it had been given it's possible the confidence of the team would have been up and it would have been possible to try and win the match in the final 30 minutes.
"We were confident after Newcastle but this was difficult and it is frustrating.
"Things aren't going well and the critical moments are going against us."