Big Doc came back into defence after sitting out Thursday's 0-0 draw against Romania and could do little as Nigeria ran out 3-0 winners at The Valley. Chances were few and far between for Robbie at the other end.
The pair have a couple of days to recover before Ireland's second and final Unity Cup game against Jamaica at The Valley onWednesday.
Meanwhile, Fredi Kanoute's Mali drew 0-0 against Morocco in a friendly on Friday.
Robbie Keane and Gary Doherty both played as Republic of Ireland were beaten by Nigeria in the Unity Cup at Charlton on Saturday.