Guzan replaced Shay Given for Villa’s 1-1 draw at Newcastle on September 2 and has worn the goalkeeper’s jersey since then.
Capped 20 times by the USA, Guzan made his name in the MLS with Chicago Fire and Chivas USA before joining Villa – as Brad Friedel’s number two – in 2008.
Now he’s number one and set to face Clint, who would love to follow his first Spurs goal – the winner at Old Trafford last week – with his first at the Lane.
“It’s good to see Brad get more starts and more minutes,” said Clint, who now has 89 USA caps to his name.
“He did really well when he was in the MLS and in the past few seasons he’s had to be the back-up.
“Now he’s trying to break through and hopefully he can because he’s a goalkeeper with real quality, he’s learned under Brad Friedel and I wish him the best.”
Naturally, that doesn’t extend to Sunday. “It doesn’t matter who I play, I’d like to score past them. It could be my mum and I’d want to score!” he added.
Look out for the full interview with Clint in Sunday’s official matchday programme – 100 pages for just £3.50.
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Supporters attending Sunday’s match at the Lane – kick-off 3pm – can take advantage of this special offer – the latest edition of Hotspur magazine and the official matchday programme for just £5!
That’s a saving of £2.95 and £5 for 184 pages of Spurs news, views and features.
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SPURS FANS OVERSEAS - VILLA BROADCAST
Here is where Sunday's match against Villa is being televised across the globe.
All times below are local times, we kick-off at 3pm GMT on Sunday.
Australia's time refers to midnight, Monday, Australian time.