It started going wrong almost from the off when City opened their account before many fans would have started to warm their seats up. The fightback did not materialise and the home side held a three-goal advantage by the break and were winning 5-0 by 10 minutes inside the second half. Jesus Navas completed the scoring in added time.
The game was less than 20 seconds old when City stole into the lead. A weak clearance from Hugo Lloris was seized upon by Sergio Aguero, who strode forward and shot powerfully goalwards. This was denied by a good save from the goalkeeper, but Younes Kaboul was not immediately alert to the loose ball and Jesus Navas beat him to it and dispatched a swirling effort into the top corner of the net.
It was a very early blow that came before any game plan would have the chance to click into gear, but the chance to level came on five minutes when a Kyle Walker run and cross resulted in a shot from Erik Lamela that was prodded away from danger by Martin Demichelis.
The lead could well have been doubled when Alvara Negredo and Aguero combined to put the Argentina international through on goal. He attempted a dink over the keeper but didn't bank on Lloris being wise to his intentions and it was a case of failed execution.
Sandro made a quite magnificent challenge on Samir Nasri as City were quick out of the blocks on the counter attack before Jan Vertonghen worked Costel Pantilimon with a low free-kick.
Vertonghen embarked on a charge towards goal on 23 minutes that caused some alarm in the home ranks.
City's lead was doubled on 33 minutes when a Nasri dart forward led to Aguero again testing Lloris, who reacted with a fine save, but the ball ran to Negredo, who smashed into the net via the legs of Kaboul and Sandro. The goal was 'credited' to Sandro.
Seven minutes later it was three when the defence was cut open with Navas delivering a low centre for Aguero to divert home.
Paulinho should have reduced the deficit moments later but wastefully shot over the bar from a promising position. Half-time was a welcome distraction.
The onset of the second half saw a return to action for Emmanuel Adebayor in place of Lewis Holtby but events took another turn for the worse five minutes into the half. Yaya Toure set off on a charge and teed up Aguero to slide the ball past Lloris. Nasri then nearly made it five with a clever shot that hit the bar.
On 54 minutes it was five when Negredo turned on the edge of the area and arrowed a superb shot past Lloris.
Mousa Dembele, introduced for Paulinho, tested Pantilimon with a low shot on 64 minutes - Gylfi Sigurdsson came on at the same time in place of Roberto Soldado.
City went close again twice with Negredo and Toure perhaps both feeling they could have done better, while there were no real signs of a comeback or consolation strike at the other end.
Adebayor was denied by Pantilimon with the clock ticking towards the 80 minute mark, but Fernandinho should certainly have scored moments later when picked out in front of goal by James Milner.
In the end, Navas had the final word, latching onto a long clearance and slotting home past Lloris.
It was not a game to remember and one to put right when the other Manchester team come to town next week.
City - Pantilmon; Zabaleta, Demichelis, Nastasic (Lescott, 46), Clichy; Navas, Fernandinho, Toure, Nasri (Milner, 78); Aguero (Garcia, 69); Negredo. Unused subs: Hart, Richards, Guidetti, Dzeko.
Spurs (4-2-3-1) - Lloris; Walker, Dawson, Kaboul, Vertonghen; Paulinho (Sigurdsson, 61), Sandro; Lennon, Holtby (Adebayor, 46), Lamela; Soldado (Dembele, 61). Unused subs: Friedel, Chiriches, Townsend, Defoe.
Goals: City - Navas (14 seconds, 90+1), Negredo (33, 55) Aguero (40, 50).
Yellow cards: City - Toure. Spurs - Sandro, Vertonghen, Walker.
Refere: Mr H Webb.