Kick-off at Carlisle's Brunton Park is 7.45pm.
Carlisle are currently 17th in League One after a 2-0 loss at MK Dons on Saturday.
They reached the third round after beating Accrington Stanley 1-0 and then coming from 1-0 down to beat Championship side Ipswich 2-1 in round two.
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For the third round draw in full - CLICK HERE...