Harry Kane fired us into the lead before a sublime 'Rabona' effort from Erik Lamela made it 2-0.
Lamela then added a third after the interval and Kane netted twice more to complete his hat-trick - before donning the goalkeeper's gloves at the other end following the late dismissal of Hugo Lloris with all three allowed substitutes already deployed.
Kane couldn't keep out Jeronimo Barrales’ free-kick - but it was a mere consolation for the visitors.
Spurs (4-2-3-1): Lloris, Dier, Vertonghen, Fazio, Dembele, Capoue, Townsend (Lennon 83), Kane, Lamela (Eriksen 76), Adebayor (Chadli 77). Substitutes (not used): Vorm, Chiriches, Stambouli, Soldado.
Asteras (4-1-4-1): Kosicky, Lluy, Sankare, Zisopoulos, Panteliadis, Munafo, Tsokanis, Rolle (Barrales 73), Usero, Mazza (Bakasetas 82), Parra (Fernandez 80). Substitutes (not used): Theodoropoulos, Badibanga, Gianniotas, Kiriakopoulos.
Goals: Spurs – Kane 13, 75, 81, Lamela 29, 66; Asteras – Barrales 89.
Yellow card: Asteras – Panteliadis.
Red card: Spurs - Lloris.
Referee: Ivan Kruzliak.