Goals from Andros Townsend and Harry Kane in the first half secured the victory.
Asteras - unbeaten at home in Europe beforehand - put us under pressure in the second half and replied late when Federico Fazio was penalised for a foul on Jeronimo Barrales in the box, a penalty was awarded and Federico was sent off. Barrales slotted home from the spot in the final minute as it ended 2-1 in Tripolis.
Asteras Tripolis: Kosicky; Lluy, Sankare, Zisopoulos, Panteliadis; Munafo (Gianniotas, 81), Usero, Rolle; Mazza, Parra (Barrales, 84), Tsokanis (Badibanga, 60). Substitutes (not used): Theodorooulos (GK), Fernandez, Bakasetas, Kiriakopoulos.
Spurs: Vorm; Dier, Fazio, Vertonghen (C), Davies; Dembele, Stambouli; Townsend, Eriksen (Mason, 63), Lamela (Soldado, 46); Kane (Paulinho, 77). Substitutes (not used): McGee, Chiriches, Rose, Chadli.
Goals: Spurs - Townsend (36, penalty), Kane (42). Asteras - Barrales (90, penalty).
Yellow cards: Asteras Tripolis - Sankare. Spurs - Mason.
Red card: Spurs - Fazio.
Referee: Javier Estrada (Spain).